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Prophylactic reduced-dose oral amiodarone used in people going through open up-heart surgical procedures was nicely tolerated and drastically diminished the incidence of postoperative atrial fibrillation, plus the duration and price of hospitalization. Additionally, in contrast to class I or other class III antiarrhythmic agents, oral amiodarone was not associated with an increased threat of adverse events, notably ventricular proarrhythmia.
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Preoperative oral amiodarone in individuals going through complicated cardiac surgical treatment is effectively tolerated and considerably reduces the incidence of postoperative atrial fibrillation as well as the period and price of hospitalization.